Aglatimagene Besadenovec + Prodrug and Pembrolizumab vs Docetaxel for Stage IV Non-Squamous NSCLC Progressing on Pembrolizumab (AURORA)

NCT07660094 · LuTK03 Phase 3Recruiting

Lead sponsor
Candel Therapeutics, Inc. (Industry)
Enrollment
500 (estimated)
Start date
15 Jun 2026
Primary completion
22 Oct 2031 (estimated)
Study completion
22 Oct 2031
Last update posted
22 Jun 2026

Design

Study type
Interventional
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel
Masking
None
Arms
2

Interventions

  • Aglatimagene Besadenovec Biological
  • Valacyclovir Drug
  • Pembrolizumab Biological
  • Docetaxel Drug

Conditions and primary outcome

  • Non-squamous, Non-Small Cell Lung Cancer

Primary outcome

Overall Survival (From date of randomization until date of death from any cause, assessed for a minimum of 24 months)

Posted results on ClinicalTrials.gov

Results posted on ClinicalTrials.gov: No

Results from company and journal sources

No editor-confirmed results are on record for this study.

Publications

No PubMed citation lists NCT07660094.

CT-VCA trial quality

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Data integrity

Compare what the registry, company releases, FDA documents and publications say about this study.

Drugs on HealthTrade

Source

Source: ClinicalTrials.gov, U.S. National Library of Medicine. Listing a study does not mean NLM has evaluated it.

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