A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC

NCT06908304Phase 3Recruiting

Lead sponsor
Maia Biotechnology (Industry)
Enrollment
300 (estimated)
Start date
8 Dec 2025
Primary completion
31 Jul 2027 (estimated)
Study completion
31 Dec 2027
Last update posted
12 Jan 2026

Design

Study type
Interventional
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel
Masking
None
Arms
2

Interventions

  • 6-Thio-2'-Deoxyguanosine Drug
  • Cemiplimab Drug
  • Docetaxel Drug
  • Vinorelbine Drug
  • Gemcitabine alone Drug

Conditions and primary outcome

  • Carcinoma, Non-Small -Cell Lung

Primary outcome

Overall Survival (Within 2 Years)

Posted results on ClinicalTrials.gov

Results posted on ClinicalTrials.gov: No

Results from company and journal sources

No editor-confirmed results are on record for this study.

Publications

No PubMed citation lists NCT06908304.

CT-VCA trial quality

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Data integrity

Compare what the registry, company releases, FDA documents and publications say about this study.

Drugs on HealthTrade

Source

Source: ClinicalTrials.gov, U.S. National Library of Medicine. Listing a study does not mean NLM has evaluated it.

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